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SIDT2 Rabbit pAb (bs-17485R)  
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產(chǎn)品編號 bs-17485R
英文名稱 SIDT2 Rabbit pAb
中文名稱 SIDT2蛋白抗體
別    名 SIDT-2; B930096O19; BC023957; CGI 40; DKFZp686L17253; FLJ90656; MGC36407; MGC58967; RGD1308311; SID1 transmembrane family member 2; SID1 transmembrane family, member 2; SIDT2; SIDT2_HUMAN.  
研究領(lǐng)域 腫瘤  細胞生物  通道蛋白  跨膜蛋白  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human (predicted: Mouse,Rat,Rabbit,Pig,Sheep,Cow,Zebrafish,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 93 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SIDT2: 201-300/832 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 SID-1 and SID-2 belong to the systemic RNA interference defective-1 (SID1) family of transmembrane proteins. SID-1, originally identified in C. elegans, is an 827 amino acid long protein. It localizes to the cell membrane and contains eleven transmembrane domains. This suggests that SID-1 possibly functions as a channel protein. The overexpression of SID-1 enhances double stranded RNA (dsRNA) uptake in pancreatic ductal adenocarcinoma cells. SID-2, also first identified in C. elegans, is an 832 amino acid long protein with multiple transmembrane domains. At least two isoforms exist for SID-2 due to alternative splicing. Isoform 2 contains an additional 21 amino acids after residue 387 and has an alternate sequence that is 8 amino acids shorter for residues 814 to 832 of isoform 1.

Subcellular Location:
Lysosome membrane.

Post-translational modifications:
Glycosylated.

Similarity:
Belongs to the SID1 family.

SWISS:
Q8NBJ9

Gene ID:
51092

Database links:

Entrez Gene: 51092 Human

Entrez Gene: 214597 Mouse

Entrez Gene: 315617 Rat

SwissProt: Q8NBJ9 Human

SwissProt: Q8CIF6 Mouse

SwissProt: D3ZEH5 Rat

Unigene: 712144 Human

Unigene: 379345 Mouse

Unigene: 162997 Rat



產(chǎn)品圖片
Sample: Panc-1(Human) Cell Lysate at 30 ug Primary: Anti- SIDT2 (bs-17485R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 93 kD Observed band size: 98 kD
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