| 產(chǎn)品編號 | V6702 |
| 英文名稱 | TSH Mouse mAb |
| 中文名稱 | 人促甲狀腺激素α亞基單克隆抗體 |
| 克 隆 號 | 38B1 |
| 理論分子量 | 12.2 kDa |
| 檢測分子量 | 48 |
| 細(xì)胞定位 | 分泌型蛋白 |
| 性 狀 | Lyophilized or Liquid |
| 緩 沖 液 | 0.01M PBS (pH7.4). |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] Function: Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. Subunit: Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin. Subcellular Location: Secreted. Similarity: Belongs to the glycoprotein hormones subunit alpha family. SWISS: P01215 Gene ID: 1081 Database links: Entrez Gene: 1081 Human SwissProt: P01215 Human 活性異二聚體糖蛋白激素促甲狀腺素/促甲狀腺激素/TSH、促黃體激素/促黃體生成素/LH、促卵泡素/促卵泡激素/FSH和絨毛膜促性腺激素/CG的共享α鏈。這些激素結(jié)合靶細(xì)胞上的特定受體，進(jìn)而激活下游信號通路。 |
